Supercritical Fluid Chromatography

One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by provi

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography

Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today’s pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by providing efficient and selective testing capabilities on the analytical and preparative scale. The supercritical fluid mobile phase, consisting mainly of CO2, facilitates cost reduction costs and helps the industry in meeting green chemistry standards. This book provides a comprehensive overview of the use of SFC in pharmaceutical analysis. Supercritical Fluid Chromatography reviews the use of SFC in drug-discovery applications and describes its application in drug development. When a drug is developed and brought to market, it is tested many times for impurities and degradants, enantiomeric purity, and analytical and preparative isolations—it is tested during discovery and development and for under-regulated and unregulated methodologies. The book describes the use of SFC for each of these applications and discusses more in-depth topics, such as the use of SFC in mass spectrometric and polarographic detection. The book also sheds light on the role of SFC in drug development from natural products and the advancement of SFC with new technologies and its use in pilot-scale operations as a chromatographic technique.

More Books:

Supercritical Fluid Chromatography
Language: en
Pages: 418
Authors: Gregory K. Webster
Categories: Medical
Type: BOOK - Published: 2014-02-04 - Publisher: CRC Press

Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today’s pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by providing efficient and selective
Supercritical Fluid Chromatography
Language: en
Pages: 572
Authors: Colin F. Poole
Categories: Science
Type: BOOK - Published: 2017-02-16 - Publisher: Elsevier

Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths
Supercritical Fluid Chromatography And Micro-hplc
Language: en
Pages: 300
Authors: M. Yoshioka
Categories: Science
Type: BOOK - Published: 1989 - Publisher: VSP

Books about Supercritical Fluid Chromatography And Micro-hplc
Supercritical Fluid Chromatography with Patked Columns
Language: en
Pages: 472
Authors: Klaus Anton, Claire Berger
Categories: Science
Type: BOOK - Published: 1997-09-19 - Publisher: CRC Press

From the analytical to industrial preparative scale, this work provides a praxis-oriented overview of packed column supercritical fluid chromatography. It discusses and evaluates established applications and techniques, up-to-date and promising developments, and commercial instrumentation devices for use in industry. The book also reveals possibilities for problem solving and future innovations.
Practical Supercritical Fluid Chromatography and Extraction
Language: en
Pages: 456
Authors: Thomas Caudell
Categories: Science
Type: BOOK - Published: 1999-03-08 - Publisher: CRC Press

This book explores the fundamental and practical aspects of supercritical fluid chromatography (SFC) and extraction. It discusses packed columns in SFC; detection in SFC; supercritical fluid chromatography/mass spectroscopy; and evaporative light scattering detection in SFC.

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